Shinkwin C A, Beasley N, Simo R, Rushton L, Jones N S
Department of Otorhinolaryngology, Universital Hospital, Nottingham, United Kingdom.
Rhinology. 1996 Mar;34(1):41-3.
A randomised, prospective trial to evaluate Surgicel Nu-knit with Vasolene ribbon gauze and Merocel packs, respectively. Sixty patients (36 males and 24 females) undergoing bilateral nasal surgery, each having the same procedure performed on both sides, were recruited. The mean age was 49 years (range: 16-70 years). At operation, Surgicel Nu-knit was placed in one nostril, the other nostril was randomised to Vasolene gauze or Merocel. Twenty-four hours post-operatively, patients were asked to assess the discomfort experienced in either side of the nose while the packs were in position and on removal. The length of time and estimated amount of bleeding following removal of packs were also assessed. Surgicel Nu-knit caused significantly less discomfort both while in position and on removal than Vasolene gauze (p < 0.01, respectively). Compared to Merocel sponges, Surgicel Nu-knit caused significantly less discomfort on removal (p < 0.01). Bleeding following removal was also significantly less compared to the other packs. One patient in the Surgicel group required a general anaesthetic to remove a retained pack fragment. At 6-week follow-up, no nasal complications were noted in all of the groups.
一项分别评估 Surgicel Nu-knit 与凡士林带状纱布和 Merocel 填塞物的随机前瞻性试验。招募了 60 例接受双侧鼻腔手术的患者（36 名男性和 24 名女性），每位患者两侧均进行相同的手术。平均年龄为 49 岁（范围：16 - 70 岁）。手术时，将 Surgicel Nu-knit 置于一侧鼻孔，另一侧鼻孔随机使用凡士林纱布或 Merocel。术后 24 小时，要求患者评估填塞物在位及取出时两侧鼻腔的不适感。还评估了取出填塞物后的出血时间和估计出血量。Surgicel Nu-knit 在在位及取出时引起的不适感均明显少于凡士林纱布（p 值分别 < 0.01）。与 Merocel 海绵相比，Surgicel Nu-knit 在取出时引起的不适感明显更少（p < 0.01）。与其他填塞物相比，取出后的出血也明显更少。Surgicel 组有 1 例患者需要全身麻醉以取出残留的填塞物碎片。在 6 周随访时，所有组均未发现鼻腔并发症。
