Vajtai I, Yonekawa Y, Schäuble B, Paulus W
Institute of Neuropathology, University Hospital Zürich, Switzerland.
Acta Neuropathol. 1996;91(5):549-53. doi: 10.1007/s004010050465.
A case of pigmented pilocytic astrocytoma (WHO grade I) incidentally found in a right temporopolar lobectomy specimen is reported. The patient, a 41-year-old woman, underwent surgery because of long-standing complex partial epilepsy of presumed post-traumatic origin. Using immunohistochemistry and electron microscopy, the tumor was shown to be composed of astrocytes without evidence of neurosecretory or melanocytic differentiation. The cytoplasmic pigment was identified as neuromelanin by its histochemical staining properties and ultrastructure. Although rare cases of ependymoma, subependymoma, choroid plexus papilloma and ganglioglioma with melanogenesis are on record, no melanotic astrocytoma has been described so far.
报告了1例在右颞极叶切除标本中偶然发现的毛细胞型色素性星形细胞瘤（世界卫生组织I级）。该患者为41岁女性，因长期存在的推测为创伤后起源的复杂部分性癫痫接受手术。通过免疫组织化学和电子显微镜检查，肿瘤显示由星形细胞组成，无神经分泌或黑素细胞分化的证据。根据其组织化学染色特性和超微结构，细胞质色素被鉴定为神经黑素。虽然有记录显示室管膜瘤、室管膜下瘤、脉络丛乳头状瘤和神经节胶质瘤发生黑色素生成的罕见病例，但迄今为止尚未描述过黑素性星形细胞瘤。
