Casariego E, Rodriguez A, Corredoira J C, Alonso P, Coira A, Bal M, López M J, Varela J
Department of Internal Medicine, Hospital Xeral, Lugo, Spain.
Eur J Clin Microbiol Infect Dis. 1996 Mar;15(3):194-200. doi: 10.1007/BF01591353.
In a prospective study of bacteremia caused by organisms of the Streptococcus milleri group a total of 32 adult patients were observed over a seven-year period. These patients accounted for 1.6% of all patients diagnosed as having significant bacteremia and 17% of all cases of streptococcal (nonpneumococcal) bacteremia diagnosed during the study period. Only five patients had polymicrobic bacteremia. In 31 cases, a presumed origin of infection was identified, generally oral or gastrointestinal disease. There were only six cases of nosocomial acquisition. The most common presenting symptom was prolonged fever. The following forms of presentation were documented: bacteremia with local suppurative infection (56%), bacteremia without local suppurative infection (25%), and endocarditis (19%). An associated focus of infection was found in the abdominal cavity in 20 cases (62%). The mortality rate was 12.5%. All isolates were susceptible to penicillin. Caution is necessary in interpreting a blood culture positive for Streptococcus milleri group organisms, since, unlike other viridans streptococci, they are rarely contaminants. For this reason patients with suppurative processes and/or digestive tract disease must be carefully investigated.
在一项关于米勒链球菌组细菌所致菌血症的前瞻性研究中，在七年时间里共观察了32例成年患者。这些患者占所有诊断为严重菌血症患者的1.6%，以及研究期间诊断出的所有链球菌（非肺炎球菌）菌血症病例的17%。只有5例患者为多种微生物菌血症。在31例病例中，确定了推测的感染源，通常为口腔或胃肠道疾病。医院获得性感染仅有6例。最常见的症状是持续发热。记录到以下几种表现形式：伴有局部化脓性感染的菌血症（56%）、无局部化脓性感染的菌血症（25%）和心内膜炎（19%）。在20例（62%）患者的腹腔中发现了相关感染灶。死亡率为12.5%。所有分离菌株对青霉素敏感。对于米勒链球菌组细菌血培养阳性的结果，在解读时需谨慎，因为与其他草绿色链球菌不同，它们很少是污染物。因此，对于患有化脓性疾病和/或消化道疾病的患者必须进行仔细检查。
