Mancia G, Omboni S
Cattedra di Medicina Interna, Ospedale S. Gerardo, Monza, Italy.
Clin Exp Hypertens. 1996 Apr-May;18(3-4):449-62. doi: 10.3109/10641969609088976.
Ambulatory blood pressure monitoring is frequently employed in the clinical practice to improve the diagnosis of hypertension and the appropriateness of the decision regarding initiation of antihypertensive treatment. It is also frequently employed to check the efficacy of this treatment in conditions resembling daily life. This paper will describe the effect of a number of antihypertensive drugs on ambulatory blood pressure, based on data collected by our group in the past 10 years. It will then discuss the advantages of ambulatory blood pressure in studies of efficacy of antihypertensive drugs and the importance of this approach for definition of the trough-to-peak ratio of the antihypertensive effect. Some technical and clinical problems inherent to the ambulatory blood pressure monitoring approach will also be discussed.
动态血压监测在临床实践中经常被用于改善高血压的诊断以及抗高血压治疗起始决策的合理性。它也经常被用于在类似日常生活的条件下检查这种治疗的效果。本文将基于我们团队在过去10年收集的数据，描述多种抗高血压药物对动态血压的影响。然后将讨论动态血压在抗高血压药物疗效研究中的优势以及这种方法对于定义降压效果谷峰比的重要性。还将讨论动态血压监测方法固有的一些技术和临床问题。
