Nilsson B, Pontén U, Voigt G
J Neurosurg. 1977 Aug;47(2):241-51. doi: 10.3171/jns.1977.47.2.0241.
Impact acceleration was used to elicit cerebral concussion in the albino rat. The pathophysiological response and morphological damage from the concussion were studied in groups of animals. The animals were grouped according to impact velocity (6-11 m/sec), and the threshold and different degrees of the concussive response were established. The concept of concussion as primarily a neuronal, functional disturbance was confirmed. However, this reaction was readily influenced by respiratory and circulatory changes, and morphological damage. Defined reactions could be elicited in groups of animals according to impact velocity. Thus, the model appeared well standardized for further studies of concussion pathophysiology, expressed in terms of cerebral energy metabolism and blood flow.
采用撞击加速度诱发白化大鼠脑震荡。对多组动物的脑震荡病理生理反应和形态学损伤进行了研究。根据撞击速度（6 - 11米/秒）对动物进行分组，并确定了脑震荡反应的阈值和不同程度。脑震荡主要是神经元功能紊乱这一概念得到了证实。然而，这种反应很容易受到呼吸和循环变化以及形态学损伤的影响。根据撞击速度，可以在多组动物中引发特定的反应。因此，该模型似乎为进一步研究以脑能量代谢和血流表示的脑震荡病理生理学提供了良好的标准化条件。
