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[荧光测定技术诊断胎粪吸入综合征]

[Diagnosis of meconium aspiration syndrome by fluorometry technique].

作者信息

Zang C, Yu S, Li S

机构信息

Second Clinical Hospital, Bethune University of Medical Science, Changchun.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 1995 Nov;30(11):681-3.

PMID:8745496
Abstract

OBJECTIVE

To establish a new diagnostic method of neonatal meconium aspiration syndrome (MAS).

METHODS

The fluorometry technique was used for examination of urine samples from three groups of neonates. The neonates were divided into 3 groups: Group I, MAS (n = 17); Group II, no MAS, but amniotic fluid with meconium stain (n = 24); Group III, normal control (n = 27). Urine fluorescence meconium index (UFMI) and urine meconium index (UMI) were calculated.

RESULTS

UFMI values of group I were higher than that of group II and III. The sensitivity and specificity of UFMI were 100% and 97% respectivety. However, it were 51% and 48% respectivety in UMI.

CONCLUSIONS

UFMI is an index for identification of Zn-coproporphycin, and it is a more sensitive index for diagnosis of MAS.

摘要

目的

建立一种新生儿胎粪吸入综合征(MAS)的新诊断方法。

方法

采用荧光测定技术对三组新生儿的尿液样本进行检测。将新生儿分为三组:第一组,MAS(n = 17);第二组,无MAS但羊水有胎粪污染(n = 24);第三组,正常对照组(n = 27)。计算尿荧光胎粪指数(UFMI)和尿胎粪指数(UMI)。

结果

第一组的UFMI值高于第二组和第三组。UFMI的敏感性和特异性分别为100%和97%。然而,UMI的敏感性和特异性分别为51%和48%。

结论

UFMI是鉴定锌原卟啉的指标,是诊断MAS更敏感的指标。

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[Diagnosis of meconium aspiration syndrome by fluorometry technique].[荧光测定技术诊断胎粪吸入综合征]
Zhonghua Fu Chan Ke Za Zhi. 1995 Nov;30(11):681-3.
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[Study on the specific diagnosis of meconium aspiration syndrome (MAS) with fluorometry].
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