Ito Y, Donahoe P K, Hendren W H
J Pediatr Surg. 1977 Jun;12(3):477-82. doi: 10.1016/0022-3468(77)90027-6.
Twenty unselected premature and perinatal infants, and 40 older infants and children with chronic constipation were investigated manometrically. Anorectal pressure studies were found to be a safe and reliable screening method for Hirschsprung's disease. Many unnecessary deep and superficial rectal biopsies were avoided by recording a normal rectoanal response. Failure to record a normal reflex requires further evaluation by tissue diagnosis. A normal reflex does not occur in premature or perinatal infants in whom maturational age (gestational age plus age after birth) has yet to reach 39 wk, and who weigh less than 6 lb.
对20名未经挑选的早产和围产期婴儿,以及40名患有慢性便秘的较大婴儿和儿童进行了测压研究。发现肛门直肠压力研究是一种用于诊断先天性巨结肠症的安全可靠的筛查方法。通过记录正常的直肠肛门反应,避免了许多不必要的深部和浅表直肠活检。未能记录到正常反射需要通过组织诊断进行进一步评估。成熟年龄(胎龄加出生后年龄)尚未达到39周且体重小于6磅的早产或围产期婴儿不会出现正常反射。