Yamane H, Nakagawa T, Iguchi H, Shibata S, Takayama M, Nishimura K, Nakai Y
Department of Otolaryngology, Osaka City University Medical School, Japan.
Acta Otolaryngol Suppl. 1995;520 Pt 1:174-7.
Recent studies have shown that inner ear sensory cells may regenerate in mammals as well as in birds. In this in vivo study we investigated the regeneration of vestibular hair cells in guinea pigs after gentamycin intoxication, and found that the vestibular sensory epithelia reproduced new hair cells 30 days after degeneration, due to 30 consecutive days of gentamycin treatment. From the regeneration pattern of sensory epithelia, the supporting cells were identified as the progenitors of hair cells.
最近的研究表明，内耳感觉细胞在哺乳动物和鸟类中都可能再生。在这项体内研究中，我们调查了庆大霉素中毒后豚鼠前庭毛细胞的再生情况，发现由于连续30天使用庆大霉素治疗，前庭感觉上皮在变性30天后再生出了新的毛细胞。从感觉上皮的再生模式来看，支持细胞被确定为毛细胞的祖细胞。
