Robinson D, Kawamura T, Hinohara S, Sakamoto Y, Takahashi T
BUPA Medical Research, Battle Bridge House, London, UK.
J Cardiovasc Risk. 1995 Oct;2(5):449-58. doi: 10.1177/174182679500200510.
We set out to compare levels of cardiovascular risk factors (blood pressure, body mass and serum lipids) in Japanese people living in the UK with those of Japanese people living in Japan and also with residents of the UK.
Blood samples were taken from individuals attending routine health screening at three centres. The study group comprised 879 men and 723 women born in Japan but living in the UK; 21 248 Japanese men and 8282 Japanese women living in Japan; and 46 623 Caucasian men and 4914 Caucasian women living in the UK.
In both men and women we found significantly higher mean blood pressures and cholesterol levels and lower mean triglyceride levels in the expatriate Japanese compared with those still living in Japan. These differences were independent of exercise, smoking and drinking habits and were not related to self-reported levels of stress. They were present even in those Japanese who had been living in the UK for less than 1 year. Higher cholesterol levels were associated with consumption of a Western diet in women but not in men, whereas mean triglyceride levels were lower in men, but not women, eating Western food.
Our findings suggest that the levels of risk factors such as blood pressure and serum lipids are for the most part culturally, rather than genetically, determined.
我们着手比较居住在英国的日本人与居住在日本的日本人以及英国居民的心血管危险因素(血压、体重和血脂)水平。
从三个中心参加常规健康筛查的个体中采集血样。研究组包括879名出生在日本但居住在英国的男性和723名女性;21248名居住在日本的日本男性和8282名日本女性;以及46623名居住在英国的白种男性和4914名白种女性。
我们发现,与仍居住在日本的人相比,在英日本侨民的平均血压和胆固醇水平显著更高,平均甘油三酯水平更低。这些差异与运动、吸烟和饮酒习惯无关,也与自我报告的压力水平无关。即使是那些在英国居住不到1年的日本人也存在这些差异。在女性中,较高的胆固醇水平与西方饮食的摄入有关,而在男性中则不然,而食用西餐的男性平均甘油三酯水平较低,女性则不然。
我们的研究结果表明,血压和血脂等危险因素的水平在很大程度上是由文化而非基因决定的。