Lee K H, Park K H, Kim D M, Youn D H
Department of Ophthalmology, College of Medicine, Seoul National University, Korea.
Korean J Ophthalmol. 1996 Jun;10(1):24-8. doi: 10.3341/kjo.1996.10.1.24.
To investigate the correlation between optic nerve head configuration and visual field defects, optic nerve head analysis using confocal scanning laser tomography (Heidelberg Retina Tomograph, HRT) and automated static threshold perimetry using a Humphrey Field Analyzer (program C30-2) were performed on 81 eyes of 44 primary open-angle glaucoma (POAG) patients. The optic nerve head parameters-rim area, rim volume, mean retinal nerve fiber layer thickness, height variation contour, and third moment in contour were measured by HRT and were analyzed for correlation with visual field indices-mean deviation, and corrected pattern standard deviation. All optic nerve head parameters except HVC correlated significantly with the visual field indices; the highest correlation was between rim area and mean deviation (r = 0.6172, p < 0.00001). The rim area of the superior and inferior quadrants correlated significantly with the visual field defects in corresponding sectors. Structural optic disc measurements by HRT correlated significantly with functional optic nerve head damage in POAG.
为研究视神经乳头形态与视野缺损之间的相关性,对44例原发性开角型青光眼(POAG)患者的81只眼进行了共焦扫描激光断层扫描(海德堡视网膜断层扫描仪,HRT)分析视神经乳头以及使用Humphrey视野分析仪(程序C30-2)进行自动静态阈值视野检查。通过HRT测量视神经乳头参数——盘沿面积、盘沿体积、平均视网膜神经纤维层厚度、高度变化轮廓和轮廓的三阶矩,并分析其与视野指标——平均偏差和校正模式标准差的相关性。除高度变化轮廓(HVC)外,所有视神经乳头参数均与视野指标显著相关;盘沿面积与平均偏差之间的相关性最高(r = 0.6172,p < 0.00001)。上下象限的盘沿面积与相应扇形区域的视野缺损显著相关。HRT对视神经盘的结构测量与POAG中功能性视神经乳头损害显著相关。