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葡萄糖阻遏可能涉及具有不同糖激酶需求的过程。

Glucose repression may involve processes with different sugar kinase requirements.

作者信息

Sanz P, Nieto A, Prieto J A

机构信息

Departmento de Biotecnología de Alimentos, Instituto de Agroquímica yTecnología de Alimentos, Consejo Superior de Investigaciones Cientificas, Valencia, Spain.

出版信息

J Bacteriol. 1996 Aug;178(15):4721-3. doi: 10.1128/jb.178.15.4721-4723.1996.

DOI:10.1128/jb.178.15.4721-4723.1996
PMID:8755906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC178245/
Abstract

Adding glucose to Saccharomyces cerevisiae cells growing among nonfermentable carbon sources leads to glucose repression. This process may be resolved into several steps. An early repression response requires any one of the three glucose kinases present in S. cerevisiae (HXK1, HXK2, or GLK1). A late response is only achieved when Hxk2p is present.

摘要

向在非发酵性碳源中生长的酿酒酵母细胞添加葡萄糖会导致葡萄糖阻遏。这个过程可分为几个步骤。早期阻遏反应需要酿酒酵母中存在的三种葡萄糖激酶中的任何一种（HXK1、HXK2或GLK1）。只有当Hxk2p存在时才会出现晚期反应。

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本文引用的文献

1
Genetic analysis of glucose regulation in saccharomyces cerevisiae: control of transcription versus mRNA turnover.酿酒酵母中葡萄糖调节的遗传分析：转录控制与mRNA周转
EMBO J. 1996 Jan 15;15(2):363-74.
2
The expression of a specific 2-deoxyglucose-6P phosphatase prevents catabolite repression mediated by 2-deoxyglucose in yeast.一种特定的2-脱氧葡萄糖-6-磷酸磷酸酶的表达可防止酵母中由2-脱氧葡萄糖介导的分解代谢物阻遏。
Curr Genet. 1995 Jul;28(2):101-7. doi: 10.1007/BF00315774.
3
Lack of correlation between trehalase activation and trehalose-6 phosphate synthase deactivation in cAMP-altered mutants of Saccharomyces cerevisiae.酿酒酵母cAMP改变突变体中海藻糖酶激活与6-磷酸海藻糖合酶失活之间缺乏相关性。
Curr Genet. 1993 May-Jun;23(5-6):382-7. doi: 10.1007/BF00312622.
4
Glucose repression in fungi.真菌中的葡萄糖阻遏
Trends Genet. 1995 Jan;11(1):12-7. doi: 10.1016/s0168-9525(00)88980-5.
5
Trehalose synthase: guard to the gate of glycolysis in yeast?海藻糖合酶：酵母糖酵解之门的守护者？
Trends Biochem Sci. 1995 Jan;20(1):3-10. doi: 10.1016/s0968-0004(00)88938-0.
6
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J Bacteriol. 1983 Oct;156(1):301-7. doi: 10.1128/jb.156.1.301-307.1983.
7
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J Bacteriol. 1983 Sep;155(3):995-1000. doi: 10.1128/jb.155.3.995-1000.1983.
8
The residual enzymatic phosphorylation activity of hexokinase II mutants is correlated with glucose repression in Saccharomyces cerevisiae.己糖激酶II突变体的残余酶促磷酸化活性与酿酒酵母中的葡萄糖阻遏相关。
Mol Cell Biol. 1989 Dec;9(12):5643-9. doi: 10.1128/mcb.9.12.5643-5649.1989.
9
Structure and regulation of the multigene family controlling maltose fermentation in budding yeast.
Prog Nucleic Acid Res Mol Biol. 1989;37:281-322. doi: 10.1016/s0079-6603(08)60701-1.
10
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J Bacteriol. 1991 Mar;173(6):2045-52. doi: 10.1128/jb.173.6.2045-2052.1991.