Marder E, Calabrese R L
Volen Center, Brandeis University, Waltham, Massachusetts, USA.
Physiol Rev. 1996 Jul;76(3):687-717. doi: 10.1152/physrev.1996.76.3.687.
Rhythmic movements are produced by central pattern-generating networks whose output is shaped by sensory and neuromodulatory inputs to allow the animal to adapt its movements to changing needs. This review discusses cellular, circuit, and computational analyses of the mechanisms underlying the generation of rhythmic movements in both invertebrate and vertebrate nervous systems. Attention is paid to exploring the mechanisms by which synaptic and cellular processes interact to play specific roles in shaping motor patterns and, consequently, movement.
节律性运动由中枢模式发生器网络产生，其输出通过感觉和神经调节输入进行塑造，以使动物能够根据不断变化的需求调整其运动。本综述讨论了对无脊椎动物和脊椎动物神经系统中节律性运动产生机制的细胞、回路和计算分析。重点关注探索突触和细胞过程相互作用的机制，这些机制在塑造运动模式以及进而塑造运动方面发挥特定作用。
