Selvanayagam Z E, Gnanavendhan S G, Balakrishna K, Rao R B, Sivaraman J, Subramanian K, Puri R, Puri R K
Captain Srinivasa Murti Drug Research Institute for Ayurveda, Madras, India.
J Nat Prod. 1996 Jul;59(7):664-7. doi: 10.1021/np960355p.
Ehretianone (1), a new quinonoid xanthene, together with known sterols, was isolated from a MeOH extract of the root bark of Ehretia buxifolia. The structure of ehretianone was elucidated as 7-hydroxy-9a alpha-(3-methylbut-2-enyl)-4a alpha,9 alpha-(2-methylprop-2-enyl)-4a, 9a-dihydro-1,4-dioxoxanthene on the basis of spectroscopic data and X-ray crystallographic analysis. The antisnake venom activity of ehretianone against Echis carinatus venom in mice is also reported.
从厚叶厚壳树的根皮甲醇提取物中分离出了一种新的醌类呫吨酮化合物埃氏呫吨酮（1）以及一些已知的甾醇。基于光谱数据和X射线晶体学分析，埃氏呫吨酮的结构被确定为7-羟基-9αα-（3-甲基丁-2-烯基）-4αα，9α-（2-甲基丙-2-烯基）-4α，9α-二氢-1，4-二氧代呫吨酮。此外，还报道了埃氏呫吨酮对小鼠体内锯鳞蝰蛇毒的抗蛇毒活性。
