Cuppini C, Ambrogini P, Buffi O, Cuppini R, Ciaroni S, Cecchini T
Istituto di Anatomia e Fisiologia, University of Urbino, Italy.
Ital J Anat Embryol. 1995 Jul-Sep;100(3):135-46.
Sprouting induction by a peripheral degenerating nerve has been evaluated in normal and vitamin E-deficient rats. A piece of sural nerve was grafted close to the peroneal nerve of the same animal: at one and two months after grafting thin unmyelinated axons were visible in the graft and they were sometimes functionally active; when nerve explant was frozen before grafting, sprouting induction did not take place either in controls or in vitamin E-deficient animals. No difference was noted in sprouting induction between the two groups, while degeneration showed a different time course. Some hypotheses of possible stimuli of sprouting induction are discussed.
在正常和维生素E缺乏的大鼠中，已对周围神经退变诱导发芽进行了评估。将一段腓肠神经移植到同一只动物的腓总神经附近：移植后1个月和2个月时，在移植物中可见细的无髓轴突，它们有时具有功能活性；当在移植前将神经外植体冷冻时，无论是对照组还是维生素E缺乏的动物均未发生发芽诱导。两组之间在发芽诱导方面未观察到差异，而退变呈现出不同的时间进程。讨论了关于发芽诱导可能刺激因素的一些假说。
