Ambrogini P, Cecchini T, Ciaroni S, Del Grande P
Istituto di Scienze Morfologiche, Università di Urbino.
Boll Soc Ital Biol Sper. 1992 Oct;68(10):587-91.
Muscle reinnervation after nerve crush was observed in rats at different ages with a combined technique that simultaneously demonstrates nerve endings and endplates. At early times of reinnervation the amount of sprouting was higher in older rats than in younger rats; according to this finding an enhanced number of polyinnervated endplates was found in older rats. A similar enhancement of sprouting and polyinnervation was observed during muscle reinnervation of vitamin E deficient rats, supporting the proposed analogy between vitamin E deficiency and aging.
采用一种能同时显示神经末梢和终板的联合技术，观察了不同年龄大鼠神经挤压后的肌肉再支配情况。在再支配早期，老年大鼠的芽生数量高于年轻大鼠；根据这一发现，在老年大鼠中发现多神经支配终板的数量增加。在维生素E缺乏大鼠的肌肉再支配过程中，也观察到了类似的芽生和多神经支配增强现象，这支持了维生素E缺乏与衰老之间的类比。
