Abdul-Hadi S, Contreras R, Tombazzi C, Alvarez M, Melendez M
Institute of Tropical Medicine, Universidad Central de Venezuela, Caracas.
Rev Inst Med Trop Sao Paulo. 1996 Jan-Feb;38(1):69-73. doi: 10.1590/s0036-46651996000100013.
A well documented case of hepatic fascioliasis (HF), successfully treated with triclabendazole, is reported. Predominant clinical manifestations were fever, marked eosinophilia and abdominal pain. Triclabendazole was given as two single oral doses of 10 mg/kg each. Neither side effects nor clinical or parasitological relapses were seen after three months of follow up. Based on this experience and few other similar reports in the literature, triclabendazole might be a valid therapeutical alternative in the treatment of human fascioliasis.
本文报告了一例经三氯苯达唑成功治疗的肝片吸虫病（HF）病例，记录详实。主要临床表现为发热、显著嗜酸性粒细胞增多和腹痛。三氯苯达唑采用两次口服给药，每次剂量为10mg/kg。随访三个月后，未观察到副作用，也未出现临床或寄生虫学复发。基于这一经验以及文献中其他少数类似报告，三氯苯达唑可能是治疗人类肝片吸虫病的一种有效治疗选择。
