Sakano S, Yoshihashi Y, Miura T
Department of Orthopaedic Surgery, Nagoya University School of Medicine, Japan.
Arch Orthop Trauma Surg. 1995;114(4):237-8. doi: 10.1007/BF00444271.
Recombinant human growth hormone has recently been used to treat the short stature of Turner syndrome. However, this therapy may induce slipped capital femoral epiphysis, since the epiphyseal plate widens and becomes weak through either growth hormone or hypogonadism. This report shows that a slipped capital femoral epiphysis occurred during this treatment for an 11-year-old girl who was suffering from Turner syndrome. Thus, these patients who are being treated with growth hormone should be carefully observed.
重组人生长激素最近已被用于治疗特纳综合征的身材矮小。然而，这种疗法可能会诱发股骨头骨骺滑脱，因为生长激素或性腺功能减退会使骨骺板增宽并变得脆弱。本报告显示，一名患有特纳综合征的11岁女孩在接受这种治疗期间发生了股骨头骨骺滑脱。因此，接受生长激素治疗的这些患者应予以密切观察。
