About I, Castan B, Capdeville J, Vanche J
Service de médecine interne, hôpital de Foix, France.
Rev Med Interne. 1996;17(5):410-4. doi: 10.1016/0248-8663(96)83742-8.
RE is a well-known Gram positive bacillus which is usually pathogenic in animals. Disease in humans is rare, but incidence has clearly increased with the advent of AIDS. In humans, RE predominantly infect people with impaired cellular immunity so that it is considered an opportunistic agent. Its must common manifestation in immuno-compromised patients is a slowly progressive pneumonia which may cavitate. Even with early diagnostic and optimal and prolonged antibiotic therapy, the mortality of RE, infections remain high (20 to 55%). Problems in clinical and therapic management are illustrated in our two cases of cavitated pneumonia in two AIDS patients.
罗卡氏菌是一种著名的革兰氏阳性杆菌，通常对动物致病。人类感染该病菌的情况较为罕见，但随着艾滋病的出现，其发病率明显上升。在人类中，罗卡氏菌主要感染细胞免疫受损的人群，因此被视为一种机会性病原体。在免疫功能低下的患者中，其最常见的表现是可能形成空洞的缓慢进展性肺炎。即使进行早期诊断并给予最佳的长期抗生素治疗，罗卡氏菌感染的死亡率仍然很高（20%至55%）。我们的两例艾滋病患者发生空洞性肺炎的病例说明了临床和治疗管理中存在的问题。
