肿瘤坏死因子-α在体外刺激的猪胎儿细胞中的表达。
Expression of TNF-alpha in pig fetal cells stimulated in vitro.
作者信息
Trebichavský I, Splíchal I, Barot-Ciorbaru R
机构信息
Department of Immunology and Gnotobiology, Nový Hrádek, Czech Republic.
出版信息
Folia Microbiol (Praha). 1995;40(4):417-20. doi: 10.1007/BF02814750.
Macrophages and lymphocytes of pig fetuses stimulated in vitro with bacterial mitogens such as lipopolysaccharide and Nocardia opaca delipidated cell mitogen showed a high TNF-alpha cytoplasmic expression. TNF-alpha was detected by immunofluorescence in peripheral blood lymphocytes and lymphocytes from the thymic region as early as at 34 d of gestation. Macrophages were the main producers of TNF-alpha at later developmental stages.
用脂多糖和脱脂诺卡氏菌不透明细胞促细胞分裂剂等细菌促细胞分裂剂在体外刺激的猪胎儿巨噬细胞和淋巴细胞显示出高肿瘤坏死因子-α（TNF-α）细胞质表达。早在妊娠34天时，通过免疫荧光在外周血淋巴细胞和胸腺区域的淋巴细胞中检测到TNF-α。在发育后期，巨噬细胞是TNF-α的主要产生者。
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