Ortiz de Alemán M Y, Castañón de Martínez V
Neurol Neurocir Psiquiatr. 1977;18(1):39-51.
In 78 children (5-13 years old) with minimal brain dysfunction, a comparative trial was carried out in order to evaluate three different treatment plans: carbamazepine alone, carbamazepine plus psychotherapy and psychotherapy alone. The improvement obtained in children who received carbamazepine (alone or with psychoterapy) was greater than that of patients treated with psychotherapy only. The difference was highly statistically significant (p=0.01). Carbamazepine was well tolerated. This trial has shown that carbamazepine is a useful aid in the treatment of behavioral and learning disorders occurring in children with minimal brain dysfunction.
对78名5至13岁的轻微脑功能障碍儿童进行了一项对比试验，以评估三种不同的治疗方案：单用卡马西平、卡马西平加心理治疗以及单用心理治疗。接受卡马西平治疗（单用或联合心理治疗）的儿童所获得的改善大于仅接受心理治疗的患者。差异具有高度统计学意义（p = 0.01）。卡马西平耐受性良好。该试验表明，卡马西平有助于治疗轻微脑功能障碍儿童出现的行为和学习障碍。
