Araki K, Furuya Y, Kobayashi M, Matsuura K, Ogata T, Isozaki H
Department of Surgery, Kochi Medical School, Japan.
J Electron Microsc (Tokyo). 1996 Jun;45(3):202-6. doi: 10.1093/oxfordjournals.jmicro.a023433.
The microcirculation of the human colon with special reference to the differences in microvascular architecture between the proximal and distal colon was studied by scanning electron microscopy with vascular corrosion casting technique. The subsurface capillary networks of the ascending colon were honeycomb-like and multi-layered, with an average number of capillary layers per capillary loop of 3.28 +/- 1.10 (mean +/- SD). Whereas, those of the sigmoid colon were almost single-layered, and the average number of capillary layers was 1.19 +/- 0.39. In the cross-section of vascular casts of both parts of the colon, the ascending capillaries originating from the submucosal arterioles ascended into the mucosal layer and joined into the subsurface capillary networks, which drained into the collecting venules near the surface. The mean diameter of the collecting venules of the ascending and the sigmoid colon was 29.3 +/- 6.41 microns and 19.48 +/- 2.23 microns, respectively. From these findings, it is speculated that the multi-layered capillary networks of the proximal colon are closely related to the greater water absorption and electrolyte transport activities compared to those of the distal colon.
采用血管铸型扫描电子显微镜技术，研究了人类结肠的微循环，特别关注近端结肠和远端结肠微血管结构的差异。升结肠的黏膜下毛细血管网呈蜂窝状且多层，每个毛细血管袢的平均毛细血管层数为3.28±1.10（平均值±标准差）。而乙状结肠的黏膜下毛细血管网几乎为单层，平均毛细血管层数为1.19±0.39。在结肠这两部分的血管铸型横切面上，起源于黏膜下小动脉的升支毛细血管向上进入黏膜层并汇入黏膜下毛细血管网，后者引流至表面附近的集合小静脉。升结肠和乙状结肠集合小静脉的平均直径分别为29.3±6.41微米和19.48±2.23微米。从这些发现推测，与远端结肠相比，近端结肠的多层毛细血管网与更强的水吸收和电解质转运活动密切相关。
