van Os J, Takei N, Castle D J, Wessely S, Der G, MacDonald A M, Murray R M
Department of Psychological Medicine, King's College Hospital, London, UK.
Soc Psychiatry Psychiatr Epidemiol. 1996 Jun;31(3-4):129-36. doi: 10.1007/BF00785759.
In order to investigate conflicting reports about possible changes in the incidence of mania, we established first contact rates for mania in the defined area of Camberwell between 1965 and 1984. There was some evidence for an increase in the first contact rate of mania, especially in females. This rise may be associated with the influx into Camberwell of individuals of Afro-Caribbean origin who showed significantly higher rates than the white group [adjusted rate ratio 3.1; 95% confidence interval (CI) 1.4-6.9] and more often displayed mixed manic and schizophrenic symptomatology (risk ratio 2.2; 95% CI 1.1-4.3). We conclude that the incidence of mania has not decreased and may actually have increased. High rates of mental illness among members of ethnic minorities are not specific to schizophrenia, suggesting that a risk factor common to both manic and schizophrenic illness is more prevalent among these groups.
为了调查关于躁狂症发病率可能变化的相互矛盾的报告,我们确定了1965年至1984年坎伯韦尔特定区域内躁狂症的首次就诊率。有证据表明躁狂症的首次就诊率有所上升,尤其是在女性中。这种上升可能与非裔加勒比裔个体涌入坎伯韦尔有关,他们的发病率明显高于白人组[调整后的发病率比为3.1;95%置信区间(CI)为1.4 - 6.9],并且更常表现出混合性躁狂和精神分裂症症状(风险比为2.2;95%CI为1.1 - 4.3)。我们得出结论,躁狂症的发病率并未下降,实际上可能有所上升。少数民族成员中精神疾病的高发病率并非精神分裂症所特有,这表明躁狂症和精神分裂症共有的一个风险因素在这些群体中更为普遍。