Gullo L, Migliori M, Jadallah K, Tomassetti P
Dipartimento di Medicina Interna e Gastroenterologia, Università, Policlinico Sant'Orsola, Bologna.
Recenti Prog Med. 1996 Jun;87(6):262-6.
This review summarises the current state of knowledge regarding the risk factors for pancreatic cancer. Of all the factors studied, only smoking is well established. Excessive dietary fat and protein may increase the risk, but this has not been proven conclusively. Fruits and vegetables, on the other hand, may offer a protective effect. The role of coffee remains controversial. There is no concrete evidence that alcohol, tea, occupational exposure, diabetes, gallstones, cholecystectomy or gastrectomy are significantly associated with this tumour. A possible predisposing role for chronic pancreatitis cannot be excluded.
本综述总结了目前关于胰腺癌危险因素的知识现状。在所有研究的因素中,只有吸烟是已明确的。过多的膳食脂肪和蛋白质可能会增加风险,但这尚未得到确凿证实。另一方面,水果和蔬菜可能具有保护作用。咖啡的作用仍存在争议。没有确凿证据表明酒精、茶、职业暴露、糖尿病、胆结石、胆囊切除术或胃切除术与这种肿瘤有显著关联。不能排除慢性胰腺炎可能具有的诱发作用。