Liccardi G, Noschese P, Salzillo A, Morandi M, Calderaro F, D'Amato M, D'Amato G
Dipartimento di Malattie Respiratorie, Ospedale A. Cardarelli, Napoli.
Recenti Prog Med. 1996 May;87(5):208-12.
The aim of our study was the evaluation of the role of these insects as causative agents of perennial rhinitis. We studied 317 subjects of both sexes (175 F and 142 M) living in Naples area and examined consecutively in our Centre for perennial nasal symptoms of suspected IgE mediated aetiology. All patients underwent the following diagnostic procedures: anamnestic procedures by using an internal questionnaire, clinical examination, skin prick test by using commercially available allergenic extracts and an allergenic extract containing the whole bodies of Blattella germanica and orientalis, Periplaneta americana. Blood samples for specific IgE determinations and a rhinologic visit were also carried out in patients with cockroach skin Prick test positivity. 14 of 317 subjects, prevalently young males, presented a skin positivity to cockroach allergens. All patients showed a moderate low degree of cutaneous and a low degree of serologic sensitization to allergens of these insects. Our preliminary data seem to demonstrate a mild role of cockroaches as causative agents of perennial rhinitis in Naples area. Further studies are necessary for a more appropriate knowledge of this allergy.
我们研究的目的是评估这些昆虫作为常年性鼻炎致病因素的作用。我们对居住在那不勒斯地区的317名男女受试者（175名女性和142名男性）进行了研究，并在我们中心对疑似由IgE介导病因的常年性鼻部症状患者进行了连续检查。所有患者均接受了以下诊断程序：使用内部问卷进行问诊、临床检查、使用市售变应原提取物以及含有德国小蠊、东方蜚蠊和美洲大蠊全体的变应原提取物进行皮肤点刺试验。对蟑螂皮肤点刺试验呈阳性的患者还进行了特异性IgE测定的血液样本采集和鼻科检查。317名受试者中有14名，主要是年轻男性，对蟑螂变应原皮肤试验呈阳性。所有患者对这些昆虫变应原的皮肤致敏程度均为中度偏低，血清致敏程度较低。我们的初步数据似乎表明，在那不勒斯地区，蟑螂作为常年性鼻炎致病因素的作用较小。为了更全面地了解这种过敏，还需要进一步研究。
