Greeske K, Pohlmann B K
Klinge Pharma GmbH, München.
Fortschr Med. 1996 May 30;114(15):196-200.
Within the framework of a case observation study involving more than 800 general practitioners, more than 5,000 patients with chronic venous insufficiency (CVI) were treated with standardised horse chestnut extract and followed up at regular intervals. The evolution of the symptoms, tolerability and adverse drug reactions were recorded. All of the symptoms investigated-pain, tiredness, tension and swelling in the leg, as well as itching and the tendency towards edema-all improved markedly or disappeared completely. The results of this study show that rational treatment with horse chestnut extract represents an economical, practice-relevant therapeutic "pillar", which in comparison with compression has the additional advantage of better compliance.
在一项涉及800多名全科医生的病例观察研究框架内，对5000多名慢性静脉功能不全（CVI）患者使用标准化七叶树提取物进行治疗，并定期进行随访。记录症状的演变、耐受性和药物不良反应。所有调查的症状——腿部疼痛、疲劳、紧绷和肿胀，以及瘙痒和水肿倾向——均有明显改善或完全消失。这项研究结果表明，合理使用七叶树提取物进行治疗是一种经济、与实际相关的治疗“支柱”，与压迫疗法相比，它还有依从性更好的额外优势。
