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尼泊尔药用植物的抗病毒活性。

Antiviral activities of Nepalese medicinal plants.

作者信息

Taylor R S, Manandhar N P, Hudson J B, Towers G H

机构信息

Department of Botony, University of British Columbia, Vancouver, Canada.

出版信息

J Ethnopharmacol. 1996 Jul 5;52(3):157-63. doi: 10.1016/0378-8741(96)01409-2.

DOI:10.1016/0378-8741(96)01409-2
PMID:8771457
Abstract

In a screening of plants used traditionally in Nepal to treat diseases that could be caused by viruses, methanol extracts from 21 species were assayed for activity against three mammalian viruses: herpes simplex virus, Sindbis virus and poliovirus. Assays were performed in UV-A or visible light, as well as dark. Individual species of Hypericum, Lygodium, and Maesa exhibited impressive antiviral activities, although their selective effects on the three viruses suggested that the antiviral ingredients were different in each extract. In addition, many of the other extracts showed partial inactivation of one or more test viruses.

摘要

在对尼泊尔传统上用于治疗可能由病毒引起的疾病的植物进行的筛选中,对21种植物的甲醇提取物进行了针对三种哺乳动物病毒的活性测定:单纯疱疹病毒、辛德毕斯病毒和脊髓灰质炎病毒。测定在紫外线A或可见光以及黑暗条件下进行。金丝桃属、海金沙属和杜茎山属的个别物种表现出令人印象深刻的抗病毒活性,尽管它们对这三种病毒的选择性作用表明每种提取物中的抗病毒成分不同。此外,许多其他提取物显示出一种或多种测试病毒的部分失活。

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