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["“良性”颅内高压综合征患者脑脊液动力学参数的定量评估。2]。

[Quantitative assessment of the cerebrospinal fluid dynamic parameters in patients with the "benign" intracranial hypertension syndrome. 2].

作者信息

Gasparian S S, Tumanova A A, Shakhnovich A R, Serova N K

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1996 Apr-Jun(2):11-5.

PMID:8771756
Abstract

The development of the benign intracranial hypertensive syndrome was shown to be followed by changes in liquorodynamic parameters and elastic properties of the brain. In 99% of patients, the baseline liquor pressure was elevated by 1.5-2.5 times as compared to normal values. Resistance of liquor resorption was enhanced in 82% of cases, suggesting impaired normal liquor outflow. The increased brain elasticity gradient suggests the exhaustion of cerebrospinal compensatory potentialities and correlates with the increased liquor resorption resistance. A correlation analysis of liquorodynamic parameters by taking into account clinical signs yielded a pathogenetic scheme of the development of the benign intracranial hypertensive syndrome.

摘要

结果表明,良性颅内高压综合征的发展伴随着脑脊液动力学参数和脑弹性特性的变化。99%的患者基线脑脊液压力比正常值升高了1.5至2.5倍。82%的病例脑脊液重吸收阻力增强,提示正常脑脊液流出受损。脑弹性梯度增加表明脑脊液代偿潜力耗尽,并与脑脊液重吸收阻力增加相关。通过考虑临床症状对脑脊液动力学参数进行相关分析,得出了良性颅内高压综合征发展的发病机制。

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