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华盛顿州西雅图市斯基德路的白喉,1972 - 1975年

Diphtheria on Skid Road, Seattle, Wash., 1972-75.

作者信息

Pedersen A H, Spearman J, Tronca E, Bader M, Harnisch J

出版信息

Public Health Rep. 1977 Jul-Aug;92(4):336-42.

PMID:877208
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1432014/
Abstract

From July 1972 to December 1975, an unusual outbreak of diphtheria in Seattle, Wash., resulted in a total of 558 cases and carriers, mostly among heavy alcohol users. Skin infections were predominant. Four white men died. The highest attack rate was among native American Indians. Environmental contamination and poor personal hygience were believed to be important in continuation of the epidemic, but could not be proved. Control measures included casefinding, isolation and quarantine, sanitizing dwelling units and mass immunization with Td toxoid. The high-risk geographic area was the city's Skid Road. This area continues to be the reservoir of continuing infection, but not all population subgroups there have been at equal risk. Spread to other geographic areas of the city and county has been minimal and remains under control.

摘要

1972年7月至1975年12月,华盛顿州西雅图市暴发了一场不同寻常的白喉疫情,共出现558例病例和带菌者,其中多数是酗酒者。皮肤感染最为常见。有4名白人男性死亡。发病率最高的是美国印第安人。环境污染和个人卫生条件差被认为是疫情持续的重要因素,但未能得到证实。防控措施包括病例排查、隔离和检疫、对居住单元进行消毒以及用破伤风-白喉类毒素进行大规模免疫接种。高风险地理区域是该市的斯基德路。该区域仍是持续感染的源头,但并非所有人群亚组都面临同等风险。疫情传播至该市及该县其他地理区域的情况极少,且仍在可控范围内。

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本文引用的文献

1
Diphtheria: prevalence of inapparent infection in a nonepidemic period.白喉:非流行期隐性感染的患病率。
Am J Public Health Nations Health. 1962 Sep;52(9):1444-52. doi: 10.2105/ajph.52.9.1444.
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Isolation of Corynebacterium diphtheriae in the environment of skin carriers.在皮肤带菌者环境中白喉棒状杆菌的分离
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Cutaneous infections due to Corynebacterium diphtheriae.由白喉棒状杆菌引起的皮肤感染。
Can Med Assoc J. 1973 Feb 3;108(3):329-31.
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Diphtheria infection in North West Canada, 1969, 1970 and 1971.1969年、1970年和1971年加拿大西北部的白喉感染情况。
J Hyg (Lond). 1972 Sep;70(3):503-10. doi: 10.1017/s0022172400063087.