Glinyenko V M, Abdikarimov S T, Firsova S N, Sagamonjan E A, Kadirova R, Nuorti J P, Strebel P M
Deputy's Office, Ministry of Health, Bishkek, Kyrgyz Republic.
J Infect Dis. 2000 Feb;181 Suppl 1:S98-S103. doi: 10.1086/315547.
The Kyrgyz Republic experienced a widespread diphtheria epidemic during 1994-1998. National diphtheria surveillance and vaccination coverage information were used to describe the course of the epidemic. The epidemic began in August 1994, reached a peak in 1995 with 704 cases (incidence rate: 15.4/100,000 population) and 30 deaths, and declined to an incidence rate of 4.0/100,000 during the first 8 months of 1998. Age-specific incidence was highest in 1995 among persons 15-19 and 20-29 years old. Three rounds of mass vaccination with tetanus and diphtheria toxoids for adult use (Td) were conducted; reported coverage was 69% in 1995 and >95% in 1996 and 1997. Reported routine vaccination coverage with three doses of diphtheria toxoid by age 12 months increased from 62% in 1989 to 98% in 1997. Mass vaccination of the adult population with Td and improvements in childhood vaccination coverage played a major role in controlling the epidemic.
吉尔吉斯共和国在1994 - 1998年期间经历了一场广泛的白喉疫情。利用全国白喉监测和疫苗接种覆盖率信息来描述疫情的发展过程。疫情始于1994年8月，1995年达到高峰，有704例病例（发病率：15.4/10万人口）和30人死亡，到1998年前8个月发病率降至4.0/10万。1995年，15 - 19岁和20 - 29岁人群的年龄特异性发病率最高。开展了三轮针对成人的破伤风和白喉类毒素大规模接种（Td）；报告的接种覆盖率在1995年为69%，1996年和1997年>95%。报告的12月龄儿童三剂白喉类毒素常规接种覆盖率从1989年的62%增至1997年的98%。针对成人的Td大规模接种以及儿童接种覆盖率的提高在控制疫情方面发挥了主要作用。
