Garrett W T, Chang C W, Bleck T P
Department of Neurology, University of Virginia, Charlottesville 22908, USA.
Ann Neurol. 1996 Aug;40(2):245-6. doi: 10.1002/ana.410400218.
Thrombotic thrombocytopenic purpura (TTP) is a syndrome with numerous neurological manifestations including altered mental status and seizures. At least 10% of the patients with TTP seen at our institution had nonconvulsive status epilepticus as a cause of or associated with their altered mental status. We propose that altered mental status secondary to nonconvulsive status epilepticus requiring electroencephalographic diagnosis and antiepileptic medication occurs in a substantial proportion of patients with TTP.
血栓性血小板减少性紫癜（TTP）是一种具有多种神经学表现的综合征，包括精神状态改变和癫痫发作。在我们机构就诊的TTP患者中，至少10%存在非惊厥性癫痫持续状态，这是其精神状态改变的原因或与之相关。我们提出，在相当一部分TTP患者中会出现继发于非惊厥性癫痫持续状态的精神状态改变，这需要脑电图诊断及抗癫痫药物治疗。
