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Should patients with recent onset rheumatoid arthritis be offered genetic screening?

作者信息

Symmons D P, Ollier W E, Brennan P, Silman A J

机构信息

ARC Epidemiology Research Unit, University of Manchester, United Kingdom.

出版信息

Ann Rheum Dis. 1996 Jul;55(7):407-10. doi: 10.1136/ard.55.7.407.

DOI:10.1136/ard.55.7.407
PMID:8774156
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1010200/
Abstract
摘要

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Should patients with recent onset rheumatoid arthritis be offered genetic screening?近期发病的类风湿性关节炎患者应该接受基因筛查吗？
Ann Rheum Dis. 1996 Jul;55(7):407-10. doi: 10.1136/ard.55.7.407.
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Q J Med. 1982 Summer;51(203):336-40.
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Modeling the HLA component in rheumatoid arthritis: sensitivity to DRB1 allele frequencies.类风湿关节炎中HLA成分的建模：对DRB1等位基因频率的敏感性。
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Should patients with recent onset of rheumatoid arthritis be offered genetic screening?近期发病的类风湿性关节炎患者应该接受基因筛查吗？
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本文引用的文献

1
HLA-DR1, DR4, and DRB1 disease related subtypes in rheumatoid arthritis. Association with susceptibility but not severity in a city wide community based study.类风湿关节炎中与疾病相关的HLA - DR1、DR4和DRB1亚型。一项基于全市社区的研究显示其与易感性相关，但与疾病严重程度无关。
J Rheumatol. 1995 Nov;22(11):2027-33.
2
Early rheumatoid arthritis: time to aim for remission?早期类风湿关节炎：是时候追求病情缓解了吗？
Ann Rheum Dis. 1995 Dec;54(12):944-7. doi: 10.1136/ard.54.12.944.
3
Absence of an association between HLA-DRB1*04 and rheumatoid arthritis in newly diagnosed cases from the community.社区新诊断病例中HLA-DRB1*04与类风湿关节炎之间不存在关联。
Ann Rheum Dis. 1993 Jul;52(7):539-41. doi: 10.1136/ard.52.7.539.
4
The incidence of rheumatoid arthritis in the United Kingdom: results from the Norfolk Arthritis Register.英国类风湿性关节炎的发病率：诺福克关节炎登记处的结果
Br J Rheumatol. 1994 Aug;33(8):735-9. doi: 10.1093/rheumatology/33.8.735.
5
Genetic typing of patients with inflammatory arthritis at presentation can be used to predict outcome.炎症性关节炎患者就诊时的基因分型可用于预测预后。
Arthritis Rheum. 1994 Aug;37(8):1166-70. doi: 10.1002/art.1780370809.
6
Genetic epidemiology of rheumatoid disease.类风湿病的遗传流行病学
Br Med Bull. 1995 Apr;51(2):267-85. doi: 10.1093/oxfordjournals.bmb.a072960.
7
Epidemiological study of HLA and GM in rheumatoid arthritis and related symptoms in an open Dutch population.荷兰开放人群中类风湿关节炎及相关症状的 HLA 和 GM 的流行病学研究。
Ann Rheum Dis. 1984 Aug;43(4):613-9. doi: 10.1136/ard.43.4.613.
8
Association of HLA-DR4/Dw4 and DR2/Dw2 with radiologic changes in a prospective study of patients with rheumatoid arthritis. Preferential relationship with HLA-Dw rather than HLA-DR specificities.类风湿关节炎患者前瞻性研究中 HLA - DR4/Dw4 和 DR2/Dw2 与放射学改变的关联。与 HLA - Dw 而非 HLA - DR 特异性的优先关系。
Arthritis Rheum. 1984 Jan;27(1):20-5. doi: 10.1002/art.1780270104.
9
Effects of hydroxychloroquine and sulphasalazine on progression of joint damage in rheumatoid arthritis.羟氯喹和柳氮磺胺吡啶对类风湿关节炎关节损伤进展的影响。
Lancet. 1989 May 13;1(8646):1036-8. doi: 10.1016/s0140-6736(89)92442-2.
10
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis.共享表位假说。一种理解类风湿关节炎易感性分子遗传学的方法。
Arthritis Rheum. 1987 Nov;30(11):1205-13. doi: 10.1002/art.1780301102.