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可控温度下的人体鼻黏膜功能

Human nasal mucosal function at controlled temperatures.

作者信息

Proctor D F, Andersen I, Lundqvist G R

出版信息

Respir Physiol. 1977 Jun;30(1-2):109-24. doi: 10.1016/0034-5687(77)90025-1.

DOI:10.1016/0034-5687(77)90025-1
PMID:877442
Abstract

We exposed 16 healthy human volunteers to air temperatures ranging from 7 to 39 degrees C and measured nasal mucus flow, nasal airflow resistance, forced vital capacity, rectal and body surface temperature, and air temperature within the nasal passage. A moderate fall in nasal mucus flow rate in the anterior and middle parts of the nose was observed with temperature above or below 23 degrees C. The nasal airflow resistance decreased in warm air and tended to increase in cold air. No significant changes in forced vital capacities or rectal temperature were observed. Nasopharyngeal end inspiratory air temperatures at 23 degrees C averaged 32.6 degrees C. At environmental temperatures of 15 and 31 degrees C they average 28.1 and 32.8 degrees C, respectively. Although we found alterations in upper airway function associated with altered inspired air temperature, over the range of 32 degrees C studied these changes were of minor physiological significance.

摘要

我们让16名健康的人类志愿者暴露于7至39摄氏度的气温环境中,测量了鼻黏液流量、鼻气流阻力、用力肺活量、直肠温度和体表温度,以及鼻腔内的气温。当温度高于或低于23摄氏度时,观察到鼻前部和中部的鼻黏液流速适度下降。鼻气流阻力在温暖空气中降低,在寒冷空气中则趋于增加。用力肺活量或直肠温度未观察到显著变化。23摄氏度时鼻咽部吸气末空气温度平均为32.6摄氏度。在环境温度为15和31摄氏度时,它们分别平均为28.1和32.8摄氏度。尽管我们发现上呼吸道功能的改变与吸入空气温度的改变有关,但在所研究的32摄氏度范围内,这些变化的生理意义较小。

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