抗体诱导的人乳腺癌细胞抗原再分布及脱落
Antibody-induced antigen redistribution and shedding from human breast cancer cells.
作者信息
Nordquist R E, Anglin J H, Lerner M P
出版信息
Science. 1977 Jul 22;197(4301):366-7. doi: 10.1126/science.877557.
PMID:877557
Abstract
Cell surface antigens of human breast cancer cells undergo a rapid redistribution when bound by antibodies from cancer patients. The subsequent shedding of these antigen-antibody complexes and free antigen may be instrumental in tumor survival.
摘要
人乳腺癌细胞的细胞表面抗原在与癌症患者的抗体结合时会迅速重新分布。这些抗原 - 抗体复合物和游离抗原随后的脱落可能有助于肿瘤存活。
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