Harrad R
Bristol Eye Hospital, UK.
Eye (Lond). 1996;10 ( Pt 2):270-3. doi: 10.1038/eye.1996.57.
In amblyopia the visual input from the amblyopic eye is suppressed. The difference in contrast sensitivity between the two eyes can lead to suppression of the amblyopic eye through dichoptic masking in anisometropic amblyopia and small angle strabismus. Binocular cells in the visual cortex may also be instrumental in bringing about suppression in small angle strabismus through fusional suppression and disparity-dependent suppression. In large angle strabismus without amblyopia suppression is very powerful and is probably a modified form of binocular rivalry suppression. Which particular mechanism is operating is dependent on the pathogenesis of the amblyopia, the depth of the amblyopia and, in strabismic amblyopia, the angle of strabismus. In any given subject more than one mechanism may be operating in the different areas of the field.
在弱视中，来自弱视眼的视觉输入被抑制。在屈光参差性弱视和小角度斜视中，双眼之间对比敏感度的差异可通过双眼分视掩蔽导致弱视眼被抑制。视觉皮层中的双眼细胞也可能通过融合抑制和视差依赖性抑制在小角度斜视中产生抑制作用。在无弱视的大角度斜视中，抑制作用非常强，可能是双眼竞争抑制的一种变体形式。具体哪种机制起作用取决于弱视的发病机制、弱视的程度，以及在斜视性弱视中斜视的角度。在任何给定个体中，视野的不同区域可能有不止一种机制在起作用。
