牛磺酸作为大脑中的渗透压调节剂和神经调节剂。
Taurine as osmoregulator and neuromodulator in the brain.
作者信息
Oja S S, Saransaari P
机构信息
Tampere Brain Research Center, University of Tampere Medical School, Finland.
出版信息
Metab Brain Dis. 1996 Jun;11(2):153-64. doi: 10.1007/BF02069502.
PMID:8776717
Abstract
Taurine has been assumed to function as an osmoregulator and neuromodulator in the brain. The pertinent studies are now reviewed in an attempt to formulate a unifying hypothesis as to how taurine could simultaneously act in both roles. Neuromodulatory actions of taurine may also underlie its protective effects against neuronal overexcitation and glutamate agonist-induced neurotoxicity.
摘要
牛磺酸被认为在大脑中起着渗透调节和神经调节的作用。现将相关研究进行综述，以试图就牛磺酸如何能同时发挥这两种作用形成一个统一的假说。牛磺酸的神经调节作用也可能是其对神经元过度兴奋和谷氨酸激动剂诱导的神经毒性具有保护作用的基础。
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