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枣渣膳食纤维作为大鼠降血脂剂的研究。

Studies on date waste dietary fibers as hypolipidemic agent in rats.

作者信息

Jwanny E W, Rashad M M, Moharib S A, el Beih N M

机构信息

Biochemistry Department, National Research Centre, Cairo, Egypt.

出版信息

Z Ernahrungswiss. 1996 Mar;35(1):39-44. doi: 10.1007/BF01612026.

Abstract

Date waste dietary fibers were examined as a hypolipidemic agent. White albino rats were fed on three experimental diets: I) high carbohydrate diet free of fiber; II) and III) diets consisted of diet I substituted with 100 g/kg of date waste dietary fibers cultured with Endomycopsis fibuligera at zero time and after 60 h of culturing respectively for 8 weeks. The total lipids, total cholesterol, triglycerides and phospholipids in the liver of rats given diets II and III were significantly decreased over those rats fed the control diet throughout the feeding period (8 weeks). The highest decrease in content of all these parameters was produced by diet III. Comparing diets II and III with the control diet I, total serum lipids and low density lipoprotein cholesterol (LDL-cholesterol) were decreased by 32-48%, while serum triglycerides and total cholesterol levels were lowered in the groups fed diets II and III by 23-35% respectively. Concerning high density lipoprotein cholesterol (HDL-cholesterol), the decrease was only 2-6% in rats fed diets II and III. The highest decrease level was shown in the phospholipids content (51-56%) during all of the experimental period (8 weeks).

摘要

将椰枣渣膳食纤维作为一种降血脂剂进行了研究。给白化大鼠喂食三种实验性日粮:I)不含纤维的高碳水化合物日粮;II)和III)日粮由日粮I替代,分别用0小时和培养60小时后的100 g/kg与扣囊内孢霉培养的椰枣渣膳食纤维替代,持续8周。在整个喂养期(8周)内,喂食日粮II和III的大鼠肝脏中的总脂质、总胆固醇、甘油三酯和磷脂含量与喂食对照日粮的大鼠相比显著降低。所有这些参数含量的最大降幅是由日粮III产生的。将日粮II和III与对照日粮I相比,总血清脂质和低密度脂蛋白胆固醇(LDL-胆固醇)降低了32 - 48%,而喂食日粮II和III的组中血清甘油三酯和总胆固醇水平分别降低了23 - 35%。关于高密度脂蛋白胆固醇(HDL-胆固醇),喂食日粮II和III的大鼠中降幅仅为2 - 6%。在整个实验期(8周)内,磷脂含量的降幅最大(51 - 56%)。

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