Tonolli-Serabian I, Poet J L, Dufour M, Carasset S, Mattei J P, Roux H
Department of Rheumatology, Hopital de la Conception, Marseille, France.
Clin Rheumatol. 1996 Mar;15(2):137-42. doi: 10.1007/BF02230330.
The aim of this study was to evaluate magnetic resonance images (MRI) of the wrist of rheumatoid arthritis (RA) patients. MRI and plain X-ray of the wrists were performed in 15 patients with RA, 7 patients with another chronic inflammatory joint disease (CIJD), and 10 control subjects. Patients had only minor changes on plain X-ray. Coronal T1 weighted spin echo sequences were performed before and after an intravenous pulse of gadolinium (GD). Contiguous 3 mm thick slices were obtained. Synovitis was frequently objectivized in the two groups of patients. MRI detected far more erosions and central bone geodes than plain X-ray. Geodes were frequent among controls while cortical bone erosions were frequent in patients. Most of the erosions were enhanced after GD injection in the RA patients but not in the 2 other groups. Thus MRI is not only useful in diagnosing inflammatory changes of the wrist but also in distinguishing early stage RA from other CIJD.
本研究的目的是评估类风湿性关节炎(RA)患者手腕的磁共振成像(MRI)。对15例RA患者、7例患有其他慢性炎症性关节疾病(CIJD)的患者以及10名对照者进行了手腕的MRI和X线平片检查。患者在X线平片上仅有轻微改变。在静脉注射钆(GD)脉冲前后进行冠状面T1加权自旋回波序列检查。获得连续的3毫米厚切片。滑膜炎在两组患者中经常被客观化。MRI检测到的侵蚀和中央骨囊肿比X线平片多得多。囊肿在对照组中很常见,而皮质骨侵蚀在患者中很常见。在RA患者中,大多数侵蚀在注射GD后增强,而在其他两组中则没有。因此,MRI不仅有助于诊断手腕的炎症变化,还有助于将早期RA与其他CIJD区分开来。