Ubel P A, Loewenstein G, Scanlon D, Kamlet M
Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA.
Med Decis Making. 1996 Apr-Jun;16(2):108-16. doi: 10.1177/0272989X9601600202.
To test whether cost-effectiveness analysis and present methods of eliciting health condition "utilities" capture the public's values for health care rationing.
Two surveys of economics students. The first survey measured their utilities for three states of health, using either analog scale, standard gamble, or time tradeoff. The second survey measured their preferences, in paired rationing choices of the health states from the first survey and also compared with treatment of acutely fatal appendicitis. The rationing choices each subject faced were individualized according to his or her utility responses, so that the subject should have been indifferent between the two conditions in each rationing choice.
The analog-scale elicitation method produced significantly lower utilities than the time-tradeoff and standard-gamble methods for two of the three conditions (p < 0.001). Compared with the rationing choices, all three utility-elicitation methods placed less value on the importance of saving lives and treating more severely ill people compared with less severely ill ones (p < 0.0001). The subjects' rationing choices indicated that they placed values on treating severely ill people that were tenfold to one-hundred-thousand-fold greater than would have been predicted by their utility responses. However, the subjects' rationing choices showed internal inconsistency, as, for example, treatments that were indicated to be ten times more beneficial in one scenario were valued as one hundred times more beneficial in other scenarios.
The subjects soundly rejected the rationing choices derived from their utility responses. This suggests that people's answers to utility elicitations cannot be easily translated into social policy. However, person-tradeoff elicitations, like those given in our rationing survey, cannot be substituted for established methods of utility elicitation until they can be performed in ways that yield acceptable internal consistency.
检验成本效益分析及当前获取健康状况“效用”的方法是否体现了公众对医疗资源分配的价值观。
对经济学专业学生进行两项调查。第一项调查使用模拟量表、标准博弈法或时间权衡法测量他们对三种健康状态的效用。第二项调查测量他们在第一项调查中健康状态的配对分配选择中的偏好,同时与急性致命性阑尾炎的治疗进行比较。每个受试者面临的分配选择根据其效用反应进行个性化设置,以便受试者在每个分配选择的两种情况之间应该无差异。
在三种情况中的两种情况下,模拟量表获取方法产生的效用显著低于时间权衡法和标准博弈法(p < 0.001)。与分配选择相比,所有三种效用获取方法在拯救生命以及治疗病情较重者而非较轻者的重要性方面所赋予的价值更低(p < 0.0001)。受试者的分配选择表明,他们对治疗重症患者所赋予的价值比根据其效用反应所预测的高出10倍至10万倍。然而,受试者的分配选择显示出内部不一致性,例如,在一种情况下显示为有益程度高10倍的治疗在其他情况下被视为有益程度高100倍。
受试者坚决拒绝从其效用反应得出的分配选择。这表明人们对效用获取问题的回答不易转化为社会政策。然而,像我们在分配调查中给出的那种个人权衡获取方法,在能够以产生可接受的内部一致性的方式进行之前,不能替代既定的效用获取方法。