Sandbak T, Murison R
Department of Biological and Medical Psychology, University of Bergen, Norway.
Physiol Behav. 1996 Apr-May;59(4-5):983-9. doi: 10.1016/0031-9384(95)02173-6.
Rats with short latency to initiate burying in the defensive burying test later showed lower alcohol consumption in an ethanol preference test than animals with medium and long latencies. These short-latency, or "active" animals also had a slight tendency to develop more ulceration than the "passive" animals. In addition, there was a negative correlation between voluntary alcohol consumption and the amount of stress-induced stomach ulcers. Many researchers view active burying behaviour as an index of anxiety. Our results suggest the opposite: that passivity, rather than active burying, may be an index of anxiety and that such passive animals subsequently ingest more ethanol. The tendency of active animals to develop more ulcers than passive animals is in contradiction to earlier studies. Our interpretation is that the long-latency animals experience more fear in the defensive burying test, with increased alcohol consumption as a result. This increase in alcohol consumption gives a cumulative cytoprotective effect against stomach ulcers.
在防御性埋土试验中开始埋土潜伏期短的大鼠，在乙醇偏好试验中比潜伏期中等和长的动物表现出更低的酒精消耗量。这些潜伏期短的，或“活跃”的动物也比“被动”动物有稍微更多发生溃疡的倾向。此外，自愿酒精消耗量与应激诱导的胃溃疡数量之间存在负相关。许多研究人员将活跃的埋土行为视为焦虑的指标。我们的结果表明相反的情况：被动性而非活跃的埋土行为可能是焦虑的指标，并且这类被动动物随后摄入更多的乙醇。活跃动物比被动动物有更多发生溃疡的倾向与早期研究相矛盾。我们的解释是，潜伏期长的动物在防御性埋土试验中经历更多恐惧，结果酒精消耗量增加。酒精消耗量的这种增加对胃溃疡产生累积性细胞保护作用。
