Hunter A G, Reid C S, Pauli R M, Scott C I
Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Canada.
Am J Med Genet. 1996 Mar 1;62(1):91-7. doi: 10.1002/(SICI)1096-8628(19960301)62:1<91::AID-AJMG18>3.0.CO;2-Q.
Several pathogenetic factors, alone or in combination, may contribute to the increased frequency of respiratory complications in achondroplasia. It has been suggested that relatively small chest circumference sometimes may contribute. However, there are no published curves of chest circumference for age in achondroplasia with which to compare patients. Nor are there data relating chest circumference to overall size in achondroplasia. We present curves of chest circumference for males and females with achondroplasia from birth through age 7 years. Additional curves for chest circumference against height are also provided. Finally, we report some preliminary data regarding the possible association of chest size with respiratory signs and symptoms.
几种致病因素单独或共同作用，可能导致软骨发育不全患者呼吸道并发症的发生率增加。有人提出，相对较小的胸围有时可能起作用。然而，目前尚无已发表的软骨发育不全患者年龄与胸围的对照曲线可供患者进行比较。也没有关于软骨发育不全患者胸围与整体身材关系的数据。我们给出了软骨发育不全男性和女性从出生到7岁的胸围曲线。还提供了胸围与身高关系的附加曲线。最后，我们报告了一些关于胸围大小与呼吸道体征和症状可能关联的初步数据。
