UK-2A、B、C和D，来自链霉菌属517-02的新型抗真菌抗生素。I. 发酵、分离及生物学特性。
UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02. I. Fermentation, isolation, and biological properties.
作者信息
Ueki M, Abe K, Hanafi M, Shibata K, Tanaka T, Taniguchi M
机构信息
Faculty of Science, Osaka City University, Japan.
出版信息
J Antibiot (Tokyo). 1996 Jul;49(7):639-43. doi: 10.7164/antibiotics.49.639.
PMID:8784423
Abstract
Novel antifungal antibiotics, UK-2A, B and a mixture of C and D, were obtained from the mycelial cake of Streptomyces sp. 517-02. All of the UK-2 compounds were similar in structure to antimycin A. The antifungal activities of UK-2 compounds were as strong as that of antimycin A. However, the UK-2 compounds demonstrated weak cytotoxicity compared to antimycin A.
摘要
新型抗真菌抗生素UK-2A、B以及C和D的混合物，是从链霉菌属517-02的菌丝饼中获得的。所有UK-2化合物在结构上与抗霉素A相似。UK-2化合物的抗真菌活性与抗霉素A一样强。然而，与抗霉素A相比，UK-2化合物表现出较弱的细胞毒性。
Zotero 插件