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兔体内肠外和肠内百日咳免疫效果的比较(作者译)

[Comparison of the efficacy of parenteral and enteral pertussis immunization in the rabbit (author's transl)].

作者信息

Höfler K H, Binder B, Koch M

出版信息

Wien Klin Wochenschr. 1977 May 27;89(11):386-9.

PMID:878481
Abstract

The effects of immunization with inactivated B. pertussis were studied in the rabbit using enteral (oral and via suppositories) and parenteral immunization routes. The rise in agglutinating and complement-binding immunoglobulins in the rabbit serum was about equal following immunization by suppository and parenteral administration, but the demonstration of local immunity (immunoglobulins reacting with B. pertussis in salive) by immunofluorescence methods was observed only in the group immunized with enterally-administered B. pertussis.

摘要

在兔中研究了经肠道(口服和栓剂途径)和非肠道免疫途径用灭活百日咳杆菌进行免疫接种的效果。通过栓剂和非肠道给药免疫后,兔血清中凝集免疫球蛋白和补体结合免疫球蛋白的升高大致相同,但仅在经肠道给予百日咳杆菌免疫的组中观察到通过免疫荧光法显示的局部免疫(唾液中与百日咳杆菌反应的免疫球蛋白)。

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