通过荧光原位杂交对酸性α-葡萄糖苷酶（GAA）和胸苷激酶（TK1）进行定位和排序。
Localization and ordering of acid alpha-glucosidase (GAA) and thymidine kinase (TK1) by fluorescence in situ hybridization.
作者信息
Kuo W L, Hirschhorn R, Huie M L, Hirschhorn K
机构信息
Division of Molecular Cytometry, Department of Laboratory Medicine, University of California, San Francisco, 94143, USA.
出版信息
Hum Genet. 1996 Mar;97(3):404-6. doi: 10.1007/BF02185782.
Genomic DNA clones of human acid alpha glucosidase (GAA) and thymidine kinase (TK1) were used to map the exact location and order of these genes on human chromosome 17. Both genes were localized to the 17q25-qter band (17q25.2-q25.3), with GAA distal to TK1. They were also shown to be, respectively, distal and proximal to an anonymous cosmid (cK17.71) previously mapped to this region.
利用人类酸性α-葡萄糖苷酶（GAA）和胸苷激酶（TK1）的基因组DNA克隆来确定这些基因在人类17号染色体上的确切位置和顺序。这两个基因都定位在17q25-qter带（17q25.2-q25.3），GAA在TK1的远端。它们还分别位于先前定位到该区域的一个匿名黏粒（cK17.71）的远端和近端。
Zotero 插件