Sasaki T, Kenri T, Okazaki N, Iseki M, Yamashita R, Shintani M, Sasaki Y, Yayoshi M
Department of Safety Research on Biologics, National Institute of Health, Tokyo.
J Clin Microbiol. 1996 Feb;34(2):447-9. doi: 10.1128/jcm.34.2.447-449.1996.
Two hundred fifty strains of Mycoplasma pneumoniae isolated during the past 20 years in Japan were classified into two groups (I and II) based upon different PCR-restriction fragment length polymorphism patterns of their P1 cytadhesin genes. Clear shifts between the M. pneumoniae groups were observed but did not appear to be correlated with M. pneumoniae epidemic cycles. Patients' sera showed relatively higher levels of antiadhesin antibodies to M. pneumoniae strains homologous with the infecting strain.
在过去20年里于日本分离出的250株肺炎支原体,根据其P1黏附素基因不同的聚合酶链反应-限制性片段长度多态性模式,被分为两组(I组和II组)。观察到肺炎支原体组之间有明显变化,但似乎与肺炎支原体的流行周期无关。患者血清对与感染菌株同源的肺炎支原体菌株显示出相对较高水平的抗黏附素抗体。