视交叉上核的消融改变了地松鼠的冬眠时间。
Ablation of suprachiasmatic nucleus alters timing of hibernation in ground squirrels.
作者信息
Ruby N F, Dark J, Heller H C, Zucker I
机构信息
Department of Biological Sciences, Stanford University, CA 94305, USA.
出版信息
Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9864-8. doi: 10.1073/pnas.93.18.9864.
Abstract
Hibernation patterns were monitored continuously for 2.5 years in female squirrels that were neurologically intact or in which the hypothalamic suprachiasmatic nucleus (SCN) was completely ablated (SCNx). The number of hibernation bouts in SCNx squirrels increased by 159%, total hibernation time increased by 58%, and periodic arousals from hibernation were 47% longer in SCNx than in control squirrels; the duration of individual torpor bouts was 2 days shorter and far more variable in SCNx than in control animals. Some SCNx squirrels cycled through bouts of torpor continuously for nearly 2 years. The SCN appears to be part of the mechanism that controls the duration of the hibernation season and the temporal structure of individual torpor bouts.
摘要
对神经功能正常或下丘脑视交叉上核（SCN）完全消融（SCNx）的雌性松鼠的冬眠模式进行了连续2.5年的监测。SCNx松鼠的冬眠次数增加了159%，总冬眠时间增加了58%，且SCNx松鼠从冬眠中的周期性觉醒时间比对照松鼠长47%；SCNx松鼠单次蛰伏期的持续时间比对照动物短2天，且变化更大。一些SCNx松鼠连续经历蛰伏期近2年。视交叉上核似乎是控制冬眠季节时长和单次蛰伏期时间结构的机制的一部分。
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