Sengör F, Erdoğan K, Tuzluoğlu D, Onur S, Erol A, Sözer T
Department of Urology, Haydarpasa, Numune Hospital, Istanbul, Turkey.
Eur Urol. 1996;29(4):446-9. doi: 10.1159/000473794.
This study was performed to evaluate safety and efficacy of laser prostatectomy in the treatment of symptomatic benign prostatic hyperplasia (BPH).
Neodymium:yttrium-aluminum-garnet (YAG) visual laser ablation of the prostate was performed in 43 patients (mean age 66 +/- 11.5 years) with BPH. The mean prostatic volume was 44.7 +/- 19.7 ml. A right-angle, side-firing laser fiber (Lasersonics Ultraline) and a neodymium:YAG laser generator (Hercules 5060) were used.
There were no perioperative complications including hemorrhage and transurethral reflux syndrome. The average postoperative hospital stay was 1.3 days, and the average urethral catheterization time was 3.8 days. Thirty-two patients were evaluated 6 months after the operation. A significant improvement was found in the mean symptom score from 21.8 +/- 7.6 to 8.3 +/- 6.9 (p < 0.001). A significant decrease from 104.3 +/- 78 to 55.7 +/- 30 ml was found between the preoperative and the postoperative mean residual urine volumes (p < 0.001). The mean peak flow rate increased from 8.7 +/- 3.9 to 16.1 +/- 2.4 ml/s (p < 0.001), and the mean average flow rate increased from 4.9 +/- 2 to 10.2 +/- 2.9 ml/s (p < 0.001).
Our results indicate that laser prostatectomy is a promising alternative in the treatment of BPH.
本研究旨在评估激光前列腺切除术治疗症状性良性前列腺增生（BPH）的安全性和有效性。
对43例BPH患者（平均年龄66±11.5岁）实施钕：钇铝石榴石（YAG）直视激光前列腺切除术。平均前列腺体积为44.7±19.7ml。使用直角侧射激光光纤（Lasersonics Ultraline）和钕：YAG激光发生器（Hercules 5060）。
无围手术期并发症，包括出血和经尿道反流综合征。术后平均住院时间为1.3天，平均导尿时间为3.8天。32例患者在术后6个月接受评估。平均症状评分从21.8±7.6显著改善至8.3±6.9（p<0.001）。术前和术后平均残余尿量从104.3±78显著降至55.7±30ml（p<0.001）。平均最大尿流率从8.7±3.9增加至16.1±2.4ml/s（p<0.001），平均平均尿流率从4.9±2增加至10.2±2.9ml/s（p<0.001）。
我们的结果表明，激光前列腺切除术是治疗BPH的一种有前景的替代方法。
