从DNA损伤到细胞周期阻滞与细胞自杀：以芽殖酵母为例
From DNA damage to cell cycle arrest and suicide: a budding yeast perspective.
作者信息
Lydall D, Weinert T
机构信息
Department of Molecular and Cellular Biology, University of Arizona, Tucson 85721, USA.
出版信息
Curr Opin Genet Dev. 1996 Feb;6(1):4-11. doi: 10.1016/s0959-437x(96)90003-9.
PMID:8791492
Abstract
Eukaryotic checkpoint control genes are important for cell cycle delay, DNA repair and cell suicide after DNA is damaged. Recent studies in budding yeast show how the participation of checkpoint control proteins in DNA metabolism could lead to all three of these outcomes.
摘要
真核生物的检验点控制基因对于细胞周期延迟、DNA修复以及DNA受损后的细胞自杀至关重要。最近对芽殖酵母的研究表明检验点控制蛋白参与DNA代谢是如何导致这三种结果的。
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