Lautt W W
Am J Physiol. 1977 Jun;232(6):H652-6. doi: 10.1152/ajpheart.1977.232.6.H652.
Acute denervation of the liver did not result in changes of oxygen uptake or hemodynamics in the intact liver of the cat. Stimulation of the hepatic nerves resulted in a marked reduction of vascular conductance of the hepatic artery and portal vein (intrahepatic) resulting in almost complete cessation of arterial flow and increased portal blood pressure. The hepatic artery showed a more complete escape from the neurogenic vasoconstriction than did the portal vein. During the stable "escape phase" oxygen delivery was 86% of control, but hepatic extraction of oxygen increased so that oxygen uptake was not altered from control values. The return of oxygen consumption to normal during nerve stimulation suggests that redistribution of hepatic blood flow did not occur. In spite of arterial and portal venous blood pressure changes and changes in gut conductance, oxygen extraction of the gut did not change.
对猫的肝脏进行急性去神经支配并未导致其完整肝脏的氧摄取或血流动力学发生变化。刺激肝神经会导致肝动脉和门静脉（肝内）的血管传导显著降低，几乎导致动脉血流完全停止，并使门静脉血压升高。与门静脉相比，肝动脉对神经源性血管收缩的逃避更为完全。在稳定的“逃避期”，氧输送量为对照值的86%，但肝脏的氧摄取增加，因此氧摄取量与对照值无变化。神经刺激期间氧消耗恢复正常表明肝脏血流未发生重新分布。尽管动脉和门静脉血压发生了变化以及肠道传导发生了改变，但肠道的氧摄取并未改变。
