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英格兰北部中毒患者在急症室的就诊情况。

Presentation of poisoned patients to accident and emergency departments in the north of England.

作者信息

Thomas S H, Bevan L, Bhattacharyya S, Bramble M G, Chew K, Connolly J, Dorani B, Han K H, Horner J E, Rodgers A, Sen B, Tesfayohannes B, Wynne H, Bateman D N

机构信息

Wolfson Unit of Clinical Pharmacology, University of Newcastle upon Tyne.

出版信息

Hum Exp Toxicol. 1996 Jun;15(6):466-70. doi: 10.1177/096032719601500602.

Abstract
  1. A 12 week prospective survey of all patients of any age with confirmed or suspected poisoning presenting to six accident and emergency departments in the North East of England was performed to establish the local incidence and patterns of presentation of poisoning. 2. 945 episodes of poisoning involving 852 patients were recorded representing approximately 1.2% of all A&E presentations and suggesting an annual attendance rate of 2.7 per 1000 persons per year. 3. Attendance rates varied threefold between hospitals and were similar in males and females overall; between the ages of five and 14 attendances were more common in females (1.9 vs 0.6/10(3)/y) while between 0 and 4 y (3.1 vs 2.4) and 25 and 34 y (3.9 vs 2.9/10(3)/y) they were more common in males. 4. The median interval between poisoning and presentation was 2 h (mean 4.1 h) and only 19% of cases presented within 1 h. Presentation was most common between Friday evening and Tuesday morning and in the late afternoon and evening. 5. 6% of the patients presented more than once with poisoning during the study period and 37% had a past history of deliberate self-harm. The most common poisons involved were paracetamol (43%), opioids (15%) and benzodiazepines (15%). 6. The study illustrates the frequency of presentations of poisoning to A&E departments. The high rate of poisoning in young men and the increasing use of paracetamol are particular causes for concern.
摘要
  1. 对英格兰东北部六个急诊科所有确诊或疑似中毒的各年龄段患者进行了为期12周的前瞻性调查,以确定当地中毒的发病率和就诊模式。2. 记录了945例中毒事件,涉及852名患者,约占所有急诊就诊病例的1.2%,表明年就诊率为每1000人每年2.7例。3. 各医院之间的就诊率相差三倍,总体上男性和女性相似;5至14岁年龄段女性就诊更为常见(1.9对0.6/10³/年),而在0至4岁(3.1对2.4)和25至34岁(3.9对2.9/10³/年)年龄段男性就诊更为常见。4. 中毒与就诊之间的中位间隔时间为2小时(平均4.1小时),只有19%的病例在1小时内就诊。就诊最常见于周五晚上至周二早上以及下午晚些时候和晚上。5. 6%的患者在研究期间因中毒多次就诊,37%有故意自伤史。最常见的中毒药物是对乙酰氨基酚(43%)、阿片类药物(15%)和苯二氮䓬类药物(15%)。6. 该研究说明了急诊科中毒就诊的频率。年轻男性中毒率高以及对乙酰氨基酚使用的增加尤其令人担忧。

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