Senocak F, Karademir S, Cabuk F, Onat N, Koc S, Duman A
Dr. Sami Ulus Children's Hospital, Ankara, Turkey.
Int J Cardiol. 1996 Mar;53(3):221-6. doi: 10.1016/0167-5273(95)02535-9.
Four-hundred-and-fifteen neonates were evaluated by echocardiographic means in order to detect interatrial septal openings and were followed for a maximum time of 18 months. In 68.67% of them, interatrial septal openings were present at the first week of life. The defects were larger than 3 mm in 50.18% of these infants. At the end of the 18th month, openings persisted in 3 cases. The statistical analyses showed significant difference about the percent of closing between the groups with initial opening sizes lesser and bigger than 3 mm. Also, there was a positive correlation between the initial size and the spontaneous closure time. Spontaneous closure incidences were not different in boys and girls. In a small group of infants (4.64%), interatrial openings close forming septal aneurysms. In 12.3% of the newborns without an opening, septal aneurysms were detected during the initial evaluation.
对415例新生儿进行了超声心动图检查，以检测房间隔缺损，并对其进行了最长18个月的随访。其中68.67%的新生儿在出生第一周就存在房间隔缺损。这些婴儿中有50.18%的缺损大于3毫米。在第18个月末，有3例缺损仍持续存在。统计分析显示，初始缺损大小小于3毫米和大于3毫米的两组之间在闭合百分比方面存在显著差异。此外，初始缺损大小与自然闭合时间之间存在正相关。男孩和女孩的自然闭合发生率没有差异。在一小部分婴儿（4.64%）中，房间隔缺损闭合形成房间隔瘤。在初始评估中，12.3%的无缺损新生儿被检测出有房间隔瘤。
